PeptidesRetatrutideWeight LossLongevityHow it worksFAQContactLog in
Physician-prescribed treatment
PrescriptionU.S. Licensed PharmacyPhysician-ReviewedDaily InjectionFSA/HSACancel Anytime

MOTS-C

A 16-amino-acid mitochondrial-derived peptide that regulates metabolic homeostasis. MOTS-C activates AMPK and improves insulin sensitivity, glucose uptake, and fatty acid oxidation. It is encoded in the mitochondrial genome and plays a key role in cellular energy metabolism.

Starting at $250/mo Start Assessment
✓ U.S.-licensed providers✓ HIPAA-secure✓ Free discreet shipping✓ Ongoing care included
MOTS-C hero image
How it works

How It Works

Get started in 3 simple steps. No office visits required.

01

Complete Online Consultation

Answer a few health questions. Our board-certified physicians review your medical history and determine if MOTS-C is right for you.

02

Get Your Prescription

If approved, your prescription is sent to our partner pharmacy. Your medication is compounded fresh and shipped directly to your door.

03

Start Your Protocol

Follow your prescribed protocol at home. Track your progress with our app. Our care team is available 24/7 for support and dose adjustments.

Why MOTS-C

Why Patients Choose MOTS-C

Advanced peptide therapy for targeted healing and optimization.

Metabolic Boost

Activates AMPK for improved energy metabolism

Insulin Sensitivity

Supports healthy glucose uptake and utilization

Fat Oxidation

Promotes fatty acid burning for energy

Cellular Energy

Enhances mitochondrial function at the cellular level

Clinical evidence

Clinical Evidence

Preclinical results demonstrating efficacy and safety.

Metabolic Research

Preclinical studies demonstrate MOTS-C effects on metabolic regulation and insulin sensitivity.

Mechanism

How MOTS-C Works

Mechanism of Action

AMPK Activation

MOTS-C activates AMP-activated protein kinase for metabolic regulation

Glucose Uptake

Enhances cellular glucose uptake and utilization

Fatty Acid Oxidation

Promotes mitochondrial fat burning for energy production

Safety

Safety Information

Important information about MOTS-C safety and side effects.

Safety InformationImportant Safety Information Warnings Compounded prescription preparation — not FDA-approved for this indication Monitor blood glucose if diabetic Store refrigerated Common Side Effects Mild injection site reaction Temporary fatigue Mild nausea
FAQ

Frequently Asked Questions

Everything you need to know about MOTS-C.

How does MOTS-C work?
MOTS-C is a mitochondrial-derived peptide that activates AMPK, the master regulator of cellular energy metabolism. It improves insulin sensitivity, enhances glucose uptake, and promotes fatty acid oxidation.
What results can I expect?
Most patients report improved energy levels and metabolic function within 2-4 weeks. Enhanced body composition and glucose regulation typically develop over 8-12 weeks.
How do I take MOTS-C?
MOTS-C is administered via subcutaneous injection 2-3x weekly. Your shipment includes pre-filled syringes and everything needed. Our care team provides injection training.
What are the side effects?
The most common side effects include mild injection site reaction, temporary fatigue, and mild nausea. These are typically mild and resolve with continued use.
Is MOTS-C FDA approved?
MOTS-C is a research peptide used under physician supervision. It is not FDA-approved for specific indications but is legally prescribed by our board-certified physicians based on clinical evidence.
Reviews

What patients are saying

Steven L.

“MOTS-C has been incredible for my energy levels. I feel more vibrant throughout the day and my blood work has improved significantly.”

March 2025

Angela R.

“After struggling with metabolic slowdown, this peptide has helped me feel like myself again. Better energy, better mood, better results.”

February 2025

Marcus T.

“My physician recommended MOTS-C as part of my longevity protocol. The metabolic improvements are measurable and I feel fantastic.”

January 2025

Ready when you are

Your assessment takes about 5 minutes. A licensed provider takes it from there.

Start Assessment
Explore

Related treatments

BPC-157 hero image

BPC-157

Physician-prescribed protocol

The "body protection compound" — accelerates tendon, ligament, and tissue recovery.

TB-500 hero image

TB-500

Physician-prescribed protocol

Thymosin Beta-4 fragment for tissue repair, flexibility, and recovery support.

GHK-Cu hero image

GHK-Cu

Physician-prescribed protocol

Copper peptide for tissue remodeling, collagen synthesis, and skin rejuvenation.

MOTS-CStarting at $250/mo
Start Assessment